LIGAND INDUCED CONFORMATIONAL CHANGES OF THE HUMAN SEROTONIN TRANSPORTER REVEALED BY MOLECULAR DYNAMICS SIMULATIONS.

Ligand induced conformational changes of the human serotonin transporter revealed by molecular dynamics simulations.

The competitive inhibitor copyright and the non-competitive inhibitor ibogaine induce different conformational states of the human serotonin transporter.It has been shown from accessibility experiments that copyright mainly induces an outward-facing conformation, while the non-competitive inhibitor ibogaine, and its active metabolite noribogaine, h

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Elevated CO2 induces down-regulation of photosynthesis and alleviates the effect of water deficit in Ceiba pentandra (Malvaceae)

ABSTRACT The simultaneous effect of elevated CO2 concentration and drought on trees is still under investigation in the Amazon.We evaluated the effect of CO2 levels (400 and 800 ppm) and water regimes (50% and 100% soil field capacity) on photosynthetic traits, chlorophyll fluorescence, and total biomass accumulation in Ceiba pentandra.In well-wate

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Optimizing SOI Slot Waveguide Fabrication Tolerances and Strip-Slot Coupling for Very Efficient Optical Sensing

Slot waveguides are becoming more and more attractive optical components, especially for chemical and bio-chemical sensing.In this paper an accurate analysis of slot waveguide fabrication tolerances is carried out, in order to find optimum design criteria for either homogeneous or absorption sensing mechanisms, in cases of low and high aspect ratio

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